Cart
sales@molnova.com
Dopamine
CAS No. 51-61-6
Dopamine( —— )
Catalog No. M24487 CAS No. 51-61-6
Dopamine is an inotropic vasopressor agent and dopamine receptor agonist used in neurological diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 49 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameDopamine
-
NoteResearch use only, not for human use.
-
Brief DescriptionDopamine is an inotropic vasopressor agent and dopamine receptor agonist used in neurological diseases.
-
DescriptionDopamine is an inotropic vasopressor agent and dopamine receptor agonist used in neurological diseases.
-
In VitroVascular permeability factor/vascular endothelial growth factor (VPF/VEGF) strongly stimulates human umbilical vein endothelial cells (HUVECs) proliferation. The stimulatory effect of VPF/VEGF is abrogated by Dopamine (1 μM; 24hours). Cell Proliferation Assay Cell Line:HUVECs Concentration:1 μMIncubation Time:24 hours Result:Inhibited VPF/VEGF-induced HUVEC proliferation specifically through its D2 receptor.
-
In VivoDopamine (50 mg/kg; i.p. injection; days 1-7) strongly and selectively inhibits the vascular permeabilizing and angiogenic activities of VPF/VEGF. Animal Model:Syngeneic C3Heb/FeJ mice with MOT ascites tumors Dosage:50 mg/kg Administration:I.p. injection; 7 days Result:Corresponding to ~5% of the median lethal dose (LD50) in mice) beginning at 24 hours after tumor-cell injection and continuing daily for 7 days.
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetDopamine Receptor
-
Recptordopamine
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number51-61-6
-
Formula Weight153.18
-
Molecular FormulaC8H11NO2
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESC1=CC(=C(C=C1CCN)O)O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Berke, Joshua D . What does dopamine mean?[J]. Nature Neuroscience, 2018.
molnova catalog
related products
-
SKF-83566
SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 nMSKF-83566 caused a concentration-dependent increase in peak single-pulse evoked extracellular DA concentration, with a maximum increase of 65% in 5 μM SKF-83566.?
-
Benperidol
Benperidol (Anquil) is a butanone analog with antipsychotic and stabilizing properties, and has been shown to be effective in blocking D2 receptors.
-
MLS1547
MLS1547 is a highly efficacious agonist of G protein-biased dopamine D2 receptor with a Ki of 1.2 μM. MLS1547 stimulates D2R G protein-mediated signaling with EC50 of 0.37 μM in a calcium mobilization assay.
