Mitraphylline( —— )

Catalog No. M24473 CAS No. 509-80-8

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Mitraphylline
Note

Research use only, not for human use.
Brief Description

Mitraphylline has antiproliferative effects on human glioma and neuroblastoma cell lines. It also has anti-inflammatory activity, it inhibits lipopolysaccharide-mediated activation of primary human neutrophils.
Description

Mitraphylline has antiproliferative effects on human glioma and neuroblastoma cell lines. It also has anti-inflammatory activity, it inhibits lipopolysaccharide-mediated activation of primary human neutrophils.
In Vitro

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In Vivo

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Synonyms

——
Pathway

Apoptosis
Target

NF-κB
Recptor

IL Receptor|NF-κB|TNF-α
Research Area

——
Indication

——

CAS Number

509-80-8
Formula Weight

368.43
Molecular Formula

C21H24N2O4
Purity

>98% (HPLC)
Solubility

DMSO:6.76 mg/mL (18.35 mM; Need ultrasonic)
SMILES

C[C@@H]([C@@H]1[C@@H]2C[C@@H]([C@@](CC3)(c(cccc4)c4N4)C4=O)N3C1)OC=C2C(OC)=O
Chemical Name

——

1.Differential alkaloid profile in Uncaria tomentosa micropropagated plantlets and root cultures.Biotechnol Lett. 2013 May;35(5):791-7.

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