Asatone
CAS No. 38451-63-7
Asatone( —— )
Catalog No. M22439 CAS No. 38451-63-7
Asatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK, and p38) pathways.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 192 | In Stock |
|
| 10MG | 286 | In Stock |
|
| 25MG | 482 | In Stock |
|
| 50MG | 687 | In Stock |
|
| 100MG | 888 | In Stock |
|
| 500MG | 1782 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAsatone
-
NoteResearch use only, not for human use.
-
Brief DescriptionAsatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK, and p38) pathways.
-
DescriptionAsatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK, and p38) pathways.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetNF-κB
-
RecptorNF-κB
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number38451-63-7
-
Formula Weight448.51
-
Molecular FormulaC24H32O8
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (222.96 mM)
-
SMILES[H][C@]12[C@H]3C(CC=C)=C[C@](OC)(C(=O)C3(OC)OC)[C@@]1(CC=C)C=C(OC)C(=O)C2(OC)OC
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
methyl chlorogenate
Methyl chlorogenate is isolated from Eriobotrya japonica which is the inhibitor of NFkappaB.
-
Polyphyllin I
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels.
-
Urolithin B
Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK.?Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.
Cart
sales@molnova.com