Boc-NH-PEG3-CH2COOH
CAS No. 462100-06-7
Boc-NH-PEG3-CH2COOH( —— )
Catalog No. M24415 CAS No. 462100-06-7
Boc-NH-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 32 | In Stock |
|
| 200MG | 48 | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameBoc-NH-PEG3-CH2COOH
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NoteResearch use only, not for human use.
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Brief DescriptionBoc-NH-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC
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DescriptionBoc-NH-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayPROTACs
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TargetPROTAC
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RecptorPEGs|Alkyl/ether
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Research Area——
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Indication——
Chemical Information
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CAS Number462100-06-7
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Formula Weight307.34
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Molecular FormulaC13H25NO7
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (325.37 mM)
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SMILESO=C(OC(C)(C)C)NCCOCCOCCOCC(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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DBCO-S-S-PEG3-biotin
DBCO-S-S-PEG3-biotin is a cleavable reagent for introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry.?The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP to remove the biotin label.?PEG Linkers can be used in the synthesis of PROTACs.
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GSK983
GSK983 (GSK-983) is a potent, cell penetrant PCAF/GCN5 PROTAC, induces concentration-dependent degradation of PCAF and GCN5 in THP1 cells with DC50 value of 1.5 nM and 3 nM, respectively.
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BETd-260 trifluoroac...
BETd-260 trifluoroacetate (ZBC260, BETd 260 TFA) is a novel PROTAC BET degrader that tether HJB97 to a ligand for the E3 ubiquitin ligase VHL.
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