Cart
sales@molnova.com
Hypophyllanthin
CAS No. 33676-00-5
Hypophyllanthin( —— )
Catalog No. M24281 CAS No. 33676-00-5
Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 159 | In Stock |
|
| 5MG | 132 | In Stock |
|
| 10MG | 217 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameHypophyllanthin
-
NoteResearch use only, not for human use.
-
Brief DescriptionHypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
-
DescriptionHypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
-
In VitroHypophyllanthin down-regulates COX-2, TNF-α, and IL-1β gene expressions in U937 macrophages by interfering with the activation of NF-κB, MAPKs, and Akt.
-
In Vivo——
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetCalcium Channel
-
RecptorCalcium Channel|P-gp|Potassium Channel
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number33676-00-5
-
Formula Weight430.5
-
Molecular FormulaC24H30O7
-
Purity>98% (HPLC)
-
SolubilityDMSO:100 mg/mL (232.29 mM; Need ultrasonic)
-
SMILESCOC[C@H](Cc1c2)[C@H](COC)[C@@H](c(cc3)cc(OC)c3OC)c1c1OCOc1c2OC
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Phyllanthin and hypophyllanthin inhibit function of P-gp but not MRP2 in Caco-2 cells.J Pharm Pharmacol. 2013 Feb;65(2):292-9.
molnova catalog
related products
-
Efonidipine
Efonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker.
-
6-Methoxyluteolin
6-Methoxyluteolin has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain.Using the human basophilic KU812F cells, we assessed the inhibitory effects of 6-Methoxyluteolin, isolated from Chrysanthemum zawadskii, in the FcαμRI-mediated allergic reaction.
-
Etripamil
Etripamil displays atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells. Etripamil is an antagonist of short-acting L-type calcium-channel.
