ICA-105574
CAS No. 316146-57-3
ICA-105574( ICA | 3-nitro-N-[4-phenoxyphenyl]-benzamide )
Catalog No. M24250 CAS No. 316146-57-3
ICA-105574 is an activator of hERG that binds to the channel to remove inactivation, thus increasing peak current amplitude and shortening the action potential. It also modulates activation kinetics of the channel.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 88 | In Stock |
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| 5MG | 80 | In Stock |
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| 10MG | 140 | In Stock |
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| 25MG | 297 | In Stock |
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| 50MG | 458 | In Stock |
|
| 100MG | 672 | In Stock |
|
| 200MG | 918 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameICA-105574
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NoteResearch use only, not for human use.
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Brief DescriptionICA-105574 is an activator of hERG that binds to the channel to remove inactivation, thus increasing peak current amplitude and shortening the action potential. It also modulates activation kinetics of the channel.
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DescriptionICA-105574 is an activator of hERG that binds to the channel to remove inactivation, thus increasing peak current amplitude and shortening the action potential. It also modulates activation kinetics of the channel.
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In Vitro——
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In Vivo——
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SynonymsICA | 3-nitro-N-[4-phenoxyphenyl]-benzamide
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PathwayAngiogenesis
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TargetEGFR
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RecptorhERG
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Research Area——
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Indication——
Chemical Information
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CAS Number316146-57-3
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Formula Weight334.33
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Molecular FormulaC19H14N2O4
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESC1=CC=C(C=C1)OC2=CC=C(C=C2)NC(=O)C3=CC(=CC=C3)[N+](=O)[O-]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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PD158780
PD 158780 reversibly inhibits auto and transphosphorylation of all four members of the ErbB receptor superfamily: EGFR ErbB2 ErbB3 and ErbB4 (IC50s: 8μM 49 nM 52 nM and 52 nM in cell assay).
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