Clobetasone butyrate

CAS No. 25122-57-0

Clobetasone butyrate( —— )

Catalog No. M24140 CAS No. 25122-57-0

Clobetasone butyrate can be used to relieve corticosteroid-responsive dermatoses, including atopic dermatitis and psoriasis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
25MG 35 In Stock
50MG 49 In Stock
100MG 71 In Stock
200MG Get Quote In Stock
500MG 170 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Clobetasone butyrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Clobetasone butyrate can be used to relieve corticosteroid-responsive dermatoses, including atopic dermatitis and psoriasis.
  • Description
    Clobetasone butyrate can be used to relieve corticosteroid-responsive dermatoses, including atopic dermatitis and psoriasis. Clobetasone butyrate is a synthetic glucocorticoid. It has topical anti-inflammatory activity especially in skin .
  • In Vitro
    ——
  • In Vivo
    Clobetasone butyrate (application on the skin; 0.05%; 7 weeks) induces epidermal thinning in skin, Clobetasone butyrate 7 weeks causes much less epidermal thinning in the pig than flurandrenolone (0.05%) or fluocinolone acetonide (0.025%), both of which causes severe atrophy. Animal Model:Large white domestic pigDosage:0.5% application on the skin Administration:7 weeks Result:Caused moderate to slight atrophy.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    glucocorticoid
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    25122-57-0
  • Formula Weight
    478.98
  • Molecular Formula
    C26H32ClFO5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:240 mg/mL (501.06 mM)
  • SMILES
    C[C@@]1(C2)[C@](C(CCl)=O)(OC(CCC)=O)[C@@H](C)C[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(F)C2=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Munro DD, et al. Clobetasone?butyrate, a?new?topical?corticosteroid:?clinical?activity?and?effects?on?pituitary-adrenal?axis?function?and?model?of?epidermal?atrophy.
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