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STM2457

CAS No. 2499663-01-1

STM2457( —— )

Catalog No. M24139 CAS No. 2499663-01-1

STM2457 is a first-in-class, highly potent, selective and orally active inhibitor of METTL3 . It can be used for the research of acute myeloid leukaemia (AML).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	225	In Stock
5MG	205	In Stock
10MG	332	In Stock
25MG	550	In Stock
50MG	770	In Stock
100MG	Get Quote	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

STM2457
Note

Research use only, not for human use.
Brief Description

STM2457 is a first-in-class, highly potent, selective and orally active inhibitor of METTL3 . It can be used for the research of acute myeloid leukaemia (AML).
Description

STM2457 is a first-in-class, highly potent, selective and orally active inhibitor of METTL3 . It can be used for the research of acute myeloid leukaemia (AML).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

METTL3
Research Area

——
Indication

——

Chemical Information

CAS Number

2499663-01-1
Formula Weight

444.53
Molecular Formula

C25H28N6O2
Purity

>98% (HPLC)
Solubility

DMSO:125 mg/mL (281.20 mM; Need ultrasonic)
SMILES

O=C(C(N=C1N2C=CC=C1)=CC2=O)NCC3=CN4C=C(CNCC5CCCCC5)C=CC4=N3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Wesley Peter Blackaby, et al. Mettl3 inhibitory compounds. WO2020201773A1.

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