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ChX710
CAS No. 2438721-44-7
ChX710( —— )
Catalog No. M24124 CAS No. 2438721-44-7
ChX710 could prime the type I interferon response to cytosolic DNA, which specific cellular Interferon-Stimulated Genes (ISGs), induces the ISRE promoter sequence, and the phosphorylation of Interferon Regulatory Factor (IRF) 3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 124 | In Stock |
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| 5MG | 112 | In Stock |
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| 10MG | 169 | In Stock |
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| 25MG | 307 | In Stock |
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| 50MG | 434 | In Stock |
|
| 100MG | 607 | In Stock |
|
| 200MG | 817 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameChX710
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NoteResearch use only, not for human use.
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Brief DescriptionChX710 could prime the type I interferon response to cytosolic DNA, which specific cellular Interferon-Stimulated Genes (ISGs), induces the ISRE promoter sequence, and the phosphorylation of Interferon Regulatory Factor (IRF) 3.
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DescriptionChX710 could prime the type I interferon response to cytosolic DNA, which specific cellular Interferon-Stimulated Genes (ISGs), induces the ISRE promoter sequence, and the phosphorylation of Interferon Regulatory Factor (IRF) 3.
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In VitroChX710 treatment is found to efficiently prime the cellular response to DNA transfection via STING as assessed by strong synergistic effects on IFN-β expression at both transcriptional and protein levels .
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetSTING
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RecptorSTING
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Research Area——
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Indication——
Chemical Information
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CAS Number2438721-44-7
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Formula Weight323.39
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Molecular FormulaC18H21N5O
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Purity>98% (HPLC)
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SolubilityDMSO:20 mg/mL (61.84 mM; Need ultrasonic)
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SMILESO=C(NC(C)CN(C)C)C1=C(N=C(C2=CC=NC=C2)N3)C3=CC=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Khiar S, et al. Identification of a small molecule that primes the type I interferon response to cytosolic DNA. Sci Rep. 2017 May 31;7(1):2561.
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