G140

CAS No. 2369751-07-3

G140( —— )

Catalog No. M24082 CAS No. 2369751-07-3

G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 176 In Stock
5MG 211 In Stock
10MG 330 In Stock
25MG 534 In Stock
50MG 783 In Stock
100MG 1079 In Stock
200MG 1451 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    G140
  • Note
    Research use only, not for human use.
  • Brief Description
    G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS).
  • Description
    G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    cGAS
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2369751-07-3
  • Formula Weight
    379.24
  • Molecular Formula
    C17H16Cl2N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:247 mg/mL?(651.30 mM;?Need ultrasonic)
  • SMILES
    OCC(N(C1)CCC(N2)=C1C3=C2C(Cl)=C(Cl)C=C3C4=NN(C)C=C4)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lama L, et, al. Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression. Nat Commun. 2019 May 21; 10(1): 2261.
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