Cart
sales@molnova.com
BAY885
CAS No. 2307249-33-6
BAY885( —— )
Catalog No. M24050 CAS No. 2307249-33-6
BAY885 is a new ERK5 inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 168 | In Stock |
|
| 5MG | 147 | In Stock |
|
| 10MG | 234 | In Stock |
|
| 25MG | 424 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBAY885
-
NoteResearch use only, not for human use.
-
Brief DescriptionBAY885 is a new ERK5 inhibitor.
-
DescriptionBAY885 is a new ERK5 inhibitor.
-
In VitroThe ERK5 probe 41 (BAY-885) showed potent ERK5 kinase and transcriptional inhibition in the SN12C-MEF2 reporter cell line (IC50 = 115 nM/IC90 = 691 nM) and had no effects on a reporter control cell line with constitutive luciferase expression (SN12C-CMV-luc, IC50 > 30 μM).
-
In Vivo——
-
Synonyms——
-
PathwayMAPK/ERK Signaling
-
TargetERK
-
RecptorERK5
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2307249-33-6
-
Formula Weight515.53
-
Molecular FormulaC25H28F3N7O2
-
Purity>98% (HPLC)
-
SolubilityDMSO:16.67 mg/mL (32.34 mM; Need ultrasonic)
-
SMILESCN1CCN(CC1)C2=CC3=C(C(=NC=N3)C4CCN(CC4)C(=O)C5=C(C=C(C=C5)OC(F)(F)F)N)N=C2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Nguyen D, et al. Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2- d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5. J Med Chem. 2019 Jan 24;62(2):928-940.
molnova catalog
related products
-
NMDA
N-Methyl-D-aspartic acid is an amino acid that, as the D-isomer, is the defining agonist for the NMDA receptor subtype of glutamate receptors.
-
ERK-IN-3
ERK-IN-3 is a potent and orally active inhibitor of ERK. It inhibits ERK1/2 with low single-digit nM IC50 values. It can be used for the research of cancers driven by RAS mutations.
-
Xanthyletin
Xanthyletin has anti-inflammatory, anti-tumor and anti-bacterial activities, it also inhibits symbiotic fungus cultivated by leaf-cutting ants.
