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Home - Products - MAPK/ERK Signaling - ERK - BAY885

BAY885

CAS No. 2307249-33-6

BAY885( —— )

Catalog No. M24050 CAS No. 2307249-33-6

BAY885 is a new ERK5 inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 168 In Stock
5MG 147 In Stock
10MG 234 In Stock
25MG 424 In Stock
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Biological Information

  • Product Name
    BAY885
  • Note
    Research use only, not for human use.
  • Brief Description
    BAY885 is a new ERK5 inhibitor.
  • Description
    BAY885 is a new ERK5 inhibitor.
  • In Vitro
    The ERK5 probe 41 (BAY-885) showed potent ERK5 kinase and transcriptional inhibition in the SN12C-MEF2 reporter cell line (IC50 = 115 nM/IC90 = 691 nM) and had no effects on a reporter control cell line with constitutive luciferase expression (SN12C-CMV-luc, IC50 > 30 μM).
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    MAPK/ERK Signaling
  • Target
    ERK
  • Recptor
    ERK5
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2307249-33-6
  • Formula Weight
    515.53
  • Molecular Formula
    C25H28F3N7O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:16.67 mg/mL (32.34 mM; Need ultrasonic)
  • SMILES
    CN1CCN(CC1)C2=CC3=C(C(=NC=N3)C4CCN(CC4)C(=O)C5=C(C=C(C=C5)OC(F)(F)F)N)N=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Nguyen D, et al. Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2- d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5. J Med Chem. 2019 Jan 24;62(2):928-940.
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