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BAY885
CAS No. 2307249-33-6
BAY885( —— )
Catalog No. M24050 CAS No. 2307249-33-6
BAY885 is a new ERK5 inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 168 | In Stock |
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| 5MG | 147 | In Stock |
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| 10MG | 234 | In Stock |
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| 25MG | 424 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBAY885
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NoteResearch use only, not for human use.
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Brief DescriptionBAY885 is a new ERK5 inhibitor.
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DescriptionBAY885 is a new ERK5 inhibitor.
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In VitroThe ERK5 probe 41 (BAY-885) showed potent ERK5 kinase and transcriptional inhibition in the SN12C-MEF2 reporter cell line (IC50 = 115 nM/IC90 = 691 nM) and had no effects on a reporter control cell line with constitutive luciferase expression (SN12C-CMV-luc, IC50 > 30 μM).
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In Vivo——
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Synonyms——
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PathwayMAPK/ERK Signaling
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TargetERK
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RecptorERK5
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Research Area——
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Indication——
Chemical Information
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CAS Number2307249-33-6
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Formula Weight515.53
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Molecular FormulaC25H28F3N7O2
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Purity>98% (HPLC)
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SolubilityDMSO:16.67 mg/mL (32.34 mM; Need ultrasonic)
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SMILESCN1CCN(CC1)C2=CC3=C(C(=NC=N3)C4CCN(CC4)C(=O)C5=C(C=C(C=C5)OC(F)(F)F)N)N=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Nguyen D, et al. Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2- d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5. J Med Chem. 2019 Jan 24;62(2):928-940.
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