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ERK-IN-3
CAS No. 2055597-12-9
ERK-IN-3( ASN007 free base )
Catalog No. M23920 CAS No. 2055597-12-9
ERK-IN-3 is a potent and orally active inhibitor of ERK. It inhibits ERK1/2 with low single-digit nM IC50 values. It can be used for the research of cancers driven by RAS mutations.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 121 | In Stock |
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| 5MG | 120 | In Stock |
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| 10MG | 174 | In Stock |
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| 25MG | 282 | In Stock |
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| 50MG | 452 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameERK-IN-3
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NoteResearch use only, not for human use.
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Brief DescriptionERK-IN-3 is a potent and orally active inhibitor of ERK. It inhibits ERK1/2 with low single-digit nM IC50 values. It can be used for the research of cancers driven by RAS mutations.
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DescriptionERK-IN-3 is a potent and orally active inhibitor of ERK. It inhibits ERK1/2 with low single-digit nM IC50 values. It can be used for the research of cancers driven by RAS mutations.
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In Vitro——
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In Vivo——
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SynonymsASN007 free base
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PathwayMAPK/ERK Signaling
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TargetERK
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RecptorERK1|ERK2
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Research Area——
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Indication——
Chemical Information
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CAS Number2055597-12-9
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Formula Weight473.93
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Molecular FormulaC22H25ClFN7O2
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Purity>98% (HPLC)
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SolubilityDMSO:250 mg/mL (527.50 mM; Need ultrasonic)
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SMILESO=C(C1=CN(C2=NC(NC3CCOCC3)=NC=C2C)C=N1)N[C@@H](C4=CC(F)=CC(Cl)=C4)CN
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sanjeeva PR, et, al. Abstract B150: ASN007, a novel oral ERK inhibitor, shows robust antitumor activity in RAS mutant cancer models. Molecular Cancer Therapeutics. 2018 Jan; 17(1).
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