C-171
CAS No. 2244881-69-2
C-171( —— )
Catalog No. M24023 CAS No. 2244881-69-2
C-171 is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
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| 10MG | 43 | In Stock |
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| 25MG | 81 | In Stock |
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| 50MG | 125 | In Stock |
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| 100MG | 193 | In Stock |
|
| 200MG | 288 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameC-171
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NoteResearch use only, not for human use.
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Brief DescriptionC-171 is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
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DescriptionC-171 is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetSTING
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RecptorSTING
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Research Area——
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Indication——
Chemical Information
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CAS Number2244881-69-2
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Formula Weight316.36
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Molecular FormulaC17H20N2O4
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESO=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C(CCCCCC)C=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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diABZI STING agonist...
diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist.
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ChX710
ChX710 could prime the type I interferon response to cytosolic DNA, which specific cellular Interferon-Stimulated Genes (ISGs), induces the ISRE promoter sequence, and the phosphorylation of Interferon Regulatory Factor (IRF) 3.
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MSA-2
MSA-2, a potent and orally available non-nucleotide STING agonist, has EC50s of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively. MSA-2 shows antitumor activity and stimulates interferon-β secretion in tumors, induces tumor regression with durable antitumor immunity, and synergizes with anti-PD-1 in syngeneic mouse tumor models.
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