Cart
sales@molnova.com
C-171
CAS No. 2244881-69-2
C-171( —— )
Catalog No. M24023 CAS No. 2244881-69-2
C-171 is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
|
| 10MG | 43 | In Stock |
|
| 25MG | 81 | In Stock |
|
| 50MG | 125 | In Stock |
|
| 100MG | 193 | In Stock |
|
| 200MG | 288 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameC-171
-
NoteResearch use only, not for human use.
-
Brief DescriptionC-171 is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
-
DescriptionC-171 is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayImmunology/Inflammation
-
TargetSTING
-
RecptorSTING
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2244881-69-2
-
Formula Weight316.36
-
Molecular FormulaC17H20N2O4
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESO=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C(CCCCCC)C=C2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Simone M Haag , Muhammet F Gulen , Luc Reymond et al. Targeting STING with covalent small-molecule inhibitors[J]. Nature, 2018.
molnova catalog
related products
-
SR-717
SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively.
-
STING agonist-1
STING agonist-1 is a human-specific STING agonistelicits antiviral activity against emerging Alphaviruses.?
-
ChX710
ChX710 could prime the type I interferon response to cytosolic DNA, which specific cellular Interferon-Stimulated Genes (ISGs), induces the ISRE promoter sequence, and the phosphorylation of Interferon Regulatory Factor (IRF) 3.
