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AB-680
CAS No. 2105904-82-1
AB-680( —— )
Catalog No. M23955 CAS No. 2105904-82-1
AB-680 is a highly potent, reversible, and selective inhibitor of CD73 (an ectonucleotidase, Ki: 4.9 pM for hCD73) with anti-tumor activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 300 | In Stock |
|
| 2MG | 155 | In Stock |
|
| 5MG | 235 | In Stock |
|
| 10MG | 373 | In Stock |
|
| 25MG | 625 | In Stock |
|
| 50MG | 871 | In Stock |
|
| 100MG | 1181 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAB-680
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NoteResearch use only, not for human use.
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Brief DescriptionAB-680 is a highly potent, reversible, and selective inhibitor of CD73 (an ectonucleotidase, Ki: 4.9 pM for hCD73) with anti-tumor activity.
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DescriptionAB-680 is a highly potent, reversible, and selective inhibitor of CD73 (an ectonucleotidase, Ki: 4.9 pM for hCD73) with anti-tumor activity, displays >10,000-fold selectivity over related ectonucleotidases CD39.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorCD73
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Research Area——
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Indication——
Chemical Information
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CAS Number2105904-82-1
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Formula Weight580.83
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Molecular FormulaC20H24ClFN4O9P2
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Purity>98% (HPLC)
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SolubilityDMSO:180 mg/mL (309.91 mM; Need ultrasonic)
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SMILESC[C@@H](c(cccc1)c1F)Nc1cc(Cl)nc2c1cnn2[C@@H]([C@@H]1O)O[C@H](COP(CP(O)(O)=O)(O)=O)[C@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Lawson KV, et al. Discovery and Characterization of AB680, a Potent and Selective Small-Molecule CD73 Inhibitor for Cancer Immunotherapy.
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