Home - Products - Others - Other Targets - AB-680

AB-680

CAS No. 2105904-82-1

AB-680( —— )

Catalog No. M23955 CAS No. 2105904-82-1

AB-680 is a highly potent, reversible, and selective inhibitor of CD73 (an ectonucleotidase, Ki: 4.9 pM for hCD73) with anti-tumor activity.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	300	In Stock
2MG	155	In Stock
5MG	235	In Stock
10MG	373	In Stock
25MG	625	In Stock
50MG	871	In Stock
100MG	1181	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

AB-680
Note

Research use only, not for human use.
Brief Description

AB-680 is a highly potent, reversible, and selective inhibitor of CD73 (an ectonucleotidase, Ki: 4.9 pM for hCD73) with anti-tumor activity.
Description

AB-680 is a highly potent, reversible, and selective inhibitor of CD73 (an ectonucleotidase, Ki: 4.9 pM for hCD73) with anti-tumor activity, displays >10,000-fold selectivity over related ectonucleotidases CD39.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

CD73
Research Area

——
Indication

——

Chemical Information

CAS Number

2105904-82-1
Formula Weight

580.83
Molecular Formula

C20H24ClFN4O9P2
Purity

>98% (HPLC)
Solubility

DMSO:180 mg/mL (309.91 mM; Need ultrasonic)
SMILES

C[C@@H](c(cccc1)c1F)Nc1cc(Cl)nc2c1cnn2[C@@H]([C@@H]1O)O[C@H](COP(CP(O)(O)=O)(O)=O)[C@H]1O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Lawson KV, et al. Discovery and Characterization of AB680, a Potent and Selective Small-Molecule CD73 Inhibitor for Cancer Immunotherapy.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

Britannilactone

Britannilactone (Desacetylinulicin) is a sesquiterpene from Inula britannica with anti-inflammatory and anti-tumor activity.Britannilactone has been associated with this antimelanotic activity and can be used in studies of skin whitening.
Secretin, porcine

Secretin, porcine (Porcine secretin acetate) is a 27-amino acid peptide, acting on pancreatic acinar cells and ductal epithelial cells stimulating the production of bicarbonate rich fluid.Secretin porcine stimulates pancreatic and gastric secretions to aid in the diagnosis of pancreatic exocrine dysfunction and the diagnosis of gastrinoma.
(2S)-2-(Benzoyloxy)b...

Benzoyl (S)-(-)-malic acid is a benzoyl malate ester compound that can be found in Medicago sativa.

Sign In Join Free