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AZ3451
CAS No. 2100284-59-9
AZ3451( —— )
Catalog No. M23951 CAS No. 2100284-59-9
AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 74 | In Stock |
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| 2MG | 36 | In Stock |
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| 5MG | 58 | In Stock |
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| 10MG | 93 | In Stock |
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| 25MG | 231 | In Stock |
|
| 50MG | 398 | In Stock |
|
| 100MG | 591 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAZ3451
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NoteResearch use only, not for human use.
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Brief DescriptionAZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).
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DescriptionAZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetPAR
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RecptorPAR-2
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Research Area——
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Indication——
Chemical Information
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CAS Number2100284-59-9
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Formula Weight571.46
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Molecular FormulaC30H27BrN4O3
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Purity>98% (HPLC)
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SolubilityDMSO: 80 mg/mL (140 mM); Water: Insoluble
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SMILESC[C@@H](C1CCCCC1)n1c(-c(cc2OCOc2c2)c2Br)nc2c1ccc(C(Nc(cc1)ccc1C#N)=O)c2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Cheng RKY, et al. Structural insight into allosteric modulation of protease-activated receptor 2. Nature. 2017 May 4;545(7652):112-115.
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