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I-191
CAS No. 1690172-25-8
I-191( —— )
Catalog No. M20654 CAS No. 1690172-25-8
I-191 is a potent antagonist of protease-activated receptor 2 (PAR2) inhibits multiple signaling functions in human cancer cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 210 | In Stock |
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| 2MG | 112 | In Stock |
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| 5MG | 188 | In Stock |
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| 10MG | 283 | In Stock |
|
| 25MG | 473 | In Stock |
|
| 50MG | 674 | In Stock |
|
| 100MG | 918 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameI-191
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NoteResearch use only, not for human use.
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Brief DescriptionI-191 is a potent antagonist of protease-activated receptor 2 (PAR2) inhibits multiple signaling functions in human cancer cells.
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DescriptionI-191 is a potent antagonist of protease-activated receptor 2 (PAR2) inhibits multiple signaling functions in human cancer cells.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetPAR
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RecptorPAR-2
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Research Area——
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Indication——
Chemical Information
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CAS Number1690172-25-8
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Formula Weight423.48
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Molecular FormulaC23H26FN5O2
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Purity>98% (HPLC)
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SolubilityDMSO:8.33 mg/mL (19.67 mM)
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SMILESCC(C)(C)c1cc(nn2cc(nc12)C(=O)N1CCNC(=O)C1(C)C)-c1ccc(F)cc1
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Chemical Name4-(8-(tert-Butyl)-6-(4-fluorophenyl)imidazo[12-b]pyridazine-2-carbonyl)-33-dimethylpiperazin-2-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Jiang Y Yau M K Lim J et al. A potent antagonist of protease-activated receptor 2 that inhibits multiple signaling functions in human cancer cells[J]. Journal of Pharmacology & Experimental Therapeutics 2018 364(2):246.
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