LSD1-IN-7 benzenesulfonate( CC-90011 benzenesulfonate )

Catalog No. M23947 CAS No. 2097523-60-7

COA

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HNMR

HPLC

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Product Name

LSD1-IN-7 benzenesulfonate
Note

Research use only, not for human use.
Brief Description

LSD1-IN-7 benzenesulfonate is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity.
Description

LSD1-IN-7 benzenesulfonate is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity.
In Vitro

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In Vivo

Animal Model:BALB/c nude mice bearing small cell lung carcinoma (SCLC)Dosage:5 mg/kg Administration:Oral administration; daily; for 30 days Result:Showed a tumor growth inhibition (TGI) of 78% at 5 mg/kg with nobody weight loss.
Synonyms

CC-90011 benzenesulfonate
Pathway

Chromatin/Epigenetic
Target

Histone Demethylase
Recptor

LSD1
Research Area

——
Indication

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CAS Number

2097523-60-7
Formula Weight

609.64
Molecular Formula

C30H29F2N5O5S
Purity

>98% (HPLC)
Solubility

DMSO:60mg/ml(98.42mM; Need ultrasonic)
SMILES

N#CC1=CC=C(C(N=C(N2CCC(N)CC2)N3C)=C(C4=CC=C(OC)C(F)=C4)C3=O)C=C1F.O=S(C5=CC=CC=C5)(O)=O
Chemical Name

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1.Young K. Chen, et al. Compositions comprising an inhibitor of lysine specific demethylase-1. WO2017079670A1.

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