Cart
sales@molnova.com
Home - Products - Endocrinology/Hormones - 5-HT Receptor - NGB2904 HCl

NGB2904 HCl

CAS No. 189060-98-8

NGB2904 HCl( NGB2904 | NGB 2904 | NGB-2904 )

Catalog No. M23863 CAS No. 189060-98-8

NGB2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 66 In Stock
2MG 32 In Stock
5MG 50 In Stock
10MG 79 In Stock
25MG 158 In Stock
50MG 273 In Stock
100MG 386 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    NGB2904 HCl
  • Note
    Research use only, not for human use.
  • Brief Description
    NGB2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively).
  • Description
    NGB2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antagonizes mitogenesis stimulated by quinpirole (IC50 = 6.8 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NGB2904 | NGB 2904 | NGB-2904
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT2|D1|D2|D3|D4|D5|α1 receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    189060-98-8
  • Formula Weight
    530.92
  • Molecular Formula
    C28H30Cl3N3O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?Ethanol : 4.55 mg/mL (9.20 mM)
  • SMILES
    O=C(c(cc1)cc(C2)c1-c1c2cccc1)NCCCCN(CC1)CCN1c1cccc(Cl)c1Cl.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hussein N, Amawi H, Karthikeyan C, Hall FS, Mittal R, Trivedi P, Ashby CR Jr, Tiwari AK. The dopamine D(3) receptor antagonists PG01037, NGB2904, SB277011A, and U99194 reverse ABCG2 transporter-mediated drug resistance in cancer cell lines. Cancer Lett. 2017 Mar 18.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • L-Stepholidine

    L-Stepholidine (Stepholidine) exhibits mixed dopamine D1 receptor agonist and D2 antagonist properties. L-Stepholidine has neuroprotective effect and inhibits Heroin-induced reinstatement. L-Stepholidine is a potential medication for the research of opiate addiction.

  • Chlorprothixene hydr...

    Chlorprothixene is a typical antipsychotic drug of the thioxanthene (tricyclic) class.

  • Lasmiditan hydrochlo...

    Lasmiditan hydrochloride is a novel centrally acting highly selective 5-HT(1F) receptor agonist (K1:2.21 μM).

Sign In Join Free