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NGB2904 HCl
CAS No. 189060-98-8
NGB2904 HCl( NGB2904 | NGB 2904 | NGB-2904 )
Catalog No. M23863 CAS No. 189060-98-8
NGB2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 51 | In Stock |
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| 5MG | 80 | In Stock |
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| 10MG | 125 | In Stock |
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| 25MG | 250 | In Stock |
|
| 50MG | 441 | In Stock |
|
| 100MG | 624 | In Stock |
|
| 500MG | 1305 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNGB2904 HCl
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NoteResearch use only, not for human use.
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Brief DescriptionNGB2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively).
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DescriptionNGB2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antagonizes mitogenesis stimulated by quinpirole (IC50 = 6.8 nM).
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In Vitro——
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In Vivo——
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SynonymsNGB2904 | NGB 2904 | NGB-2904
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT2|D1|D2|D3|D4|D5|α1 receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number189060-98-8
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Formula Weight530.92
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Molecular FormulaC28H30Cl3N3O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?Ethanol : 4.55 mg/mL (9.20 mM)
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SMILESO=C(c(cc1)cc(C2)c1-c1c2cccc1)NCCCCN(CC1)CCN1c1cccc(Cl)c1Cl.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Hussein N, Amawi H, Karthikeyan C, Hall FS, Mittal R, Trivedi P, Ashby CR Jr, Tiwari AK. The dopamine D(3) receptor antagonists PG01037, NGB2904, SB277011A, and U99194 reverse ABCG2 transporter-mediated drug resistance in cancer cell lines. Cancer Lett. 2017 Mar 18.
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