Lofepramine( Lopramine | Amplit | Leo 640 | Gamanil )

Catalog No. M26742 CAS No. 23047-25-8

Lofepramine is a potent tricyclic antidepressant that is extensively metabolized to desipramine.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	67	Get Quote
2MG	38	Get Quote
5MG	61	Get Quote
10MG	85	Get Quote
25MG	170	Get Quote
50MG	253	Get Quote
100MG	368	Get Quote
200MG	548	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Lofepramine
Note

Research use only, not for human use.
Brief Description

Lofepramine is a potent tricyclic antidepressant that is extensively metabolized to desipramine.
Description

Lofepramine is a potent tricyclic antidepressant that is extensively metabolized to desipramine. It inhibits the serotonin and norepinephrine transporters by inhibiting neurons with Kd values of 70 and 5.4 nM, respectively, with weak antagonism of serotonin, histamine and muscarinic receptors.
In Vitro

——
In Vivo

——
Synonyms

Lopramine | Amplit | Leo 640 | Gamanil
Pathway

Endocrinology/Hormones
Target

5-HT Receptor
Recptor

Topo II
Research Area

——
Indication

——

Chemical Information

CAS Number

23047-25-8
Formula Weight

418.97
Molecular Formula

C26H27ClN2O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (119.34 mM)
SMILES

CN(CCCN1c2ccccc2CCc2ccccc12)CC(=O)c1ccc(Cl)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.J P Braybrooke, et al. A phase II study of Razoxane, an antiangiogenic topoisomerase II inhibitor, in renal cell cancer with assessment of potential surrogate markers of angiogenesis. Clin Cancer Res.2000; 6(12):4697-704.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks