Cart
sales@molnova.com
Remibrutinib
CAS No. 1787294-07-8
Remibrutinib( —— )
Catalog No. M23801 CAS No. 1787294-07-8
Remibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 248 | In Stock |
|
| 5MG | 221 | In Stock |
|
| 10MG | 359 | In Stock |
|
| 25MG | 603 | In Stock |
|
| 50MG | 737 | In Stock |
|
| 100MG | 1135 | In Stock |
|
| 200MG | 1535 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameRemibrutinib
-
NoteResearch use only, not for human use.
-
Brief DescriptionRemibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood.
-
DescriptionRemibrutinib inhibits BTK activity with an IC50 value of 0.023 μM in blood. Remibrutinib is an effective and orally active Bruton tyrosine kinase inhibitor (IC50: 1 nM). Remibrutinib has the potential for Chronic urticaria (CU) treatment.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayTyrosine Kinase
-
TargetBTK
-
RecptorBTK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1787294-07-8
-
Formula Weight507.53
-
Molecular FormulaC27H27F2N5O3
-
Purity>98% (HPLC)
-
SolubilityDMSO:125 mg/mL (246.29 mM; Need ultrasonic)
-
SMILESCC1=C(C=C(C=C1NC(=O)C2=C(C=C(C=C2)C3CC3)F)F)C4=C(C(=NC=N4)N)OCCN(C)C(=O)C=C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Daniela Angst, et al. Novel amino pyrimidine derivatives. Patent WO2015079417A1.
molnova catalog
related products
-
G-744
G-744 is a highly potent, selective inhibitor of BTK with biochemical Ki of 1.28 nM.
-
JAK3/BTK-IN-1
JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two important targets in autoimmune diseases.
-
AVL-292
AVL-292 (Spebrutinib, CC-292) is a highly selective, covalent Btk inhibitor with IC50 of <1 nM; also less potently inhibits Yes, c-Src, Brk, Lyn, and Fyn with IC50s of 723 nM, 1.729 uM, 2.43 uM, 4.4 uM, and 7.15 uM, rspectively.
