BPN14770

CAS No. 1606974-33-7

BPN14770( —— )

Catalog No. M23705 CAS No. 1606974-33-7

BPN14770 is an allosteric inhibitor of selective phosphodiesterase 4D (PDE4D; IC50s: 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 144 In Stock
5MG 130 In Stock
10MG 244 In Stock
25MG 409 In Stock
50MG 551 In Stock
100MG 764 In Stock
200MG 1004 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    BPN14770
  • Note
    Research use only, not for human use.
  • Brief Description
    BPN14770 is an allosteric inhibitor of selective phosphodiesterase 4D (PDE4D; IC50s: 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3).
  • Description
    BPN14770 is an allosteric inhibitor of selective phosphodiesterase 4D (PDE4D; IC50s: 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PDE4D3|PDE4D7
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1606974-33-7
  • Formula Weight
    405.8
  • Molecular Formula
    C21H15ClF3NO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:260 mg/mL (640.71 mM; Need ultrasonic)
  • SMILES
    OC(Cc1ccc(Cc2cc(-c3cccc(Cl)c3)nc(C(F)(F)F)c2)cc1)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ricciarelli R, et al. Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer's disease. Sci Rep. 2017 Apr 12;7:46320.
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