MONNA
CAS No. 1572936-83-4
MONNA( —— )
Catalog No. M23684 CAS No. 1572936-83-4
MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 80 | In Stock |
|
| 10MG | 115 | In Stock |
|
| 25MG | 260 | In Stock |
|
| 50MG | 410 | In Stock |
|
| 100MG | 591 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameMONNA
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NoteResearch use only, not for human use.
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Brief DescriptionMONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM).
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DescriptionMONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM). It induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetChloride Channel
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RecptorTMEM16A
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Research Area——
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Indication——
Chemical Information
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CAS Number1572936-83-4
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Formula Weight338.31
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Molecular FormulaC18H14N2O5
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESCOC1=CC(=CC2=CC=CC=C21)NC3=C(C=C(C=C3)[N+](=O)[O-])C(=O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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NS1652
NS1652 is an anion conductance inhibitor. NS1652 blocks chloride channel has an IC50 of 1.6 μM in human and mouse red blood cells.NS1652 (20 μM) fully and reversibly inhibits the red cell Cl-conductance. NS1652 effectively inhibits the chloride conductance (IC50, 1.6 μM) in human and mouse red blood cells, but only weakly inhibits VRAC (IC50, 125 μM) in HEK293 cells. NS1652 markedly blocks the NO production (IC50: 3.1 μM in BV2 cells).
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T16Ainh-A01
T16Ainh-A01 is an inhibitor of the calcium-activated chloride channel TMEM16A.
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Eact
Eact is a selective and potent TMEM16A activator. It directly activates the TRPV1 channels in sensory nociceptors. Which also produces itch, acute nociception and thermal hypersensitivity.
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