Eact( —— )

Catalog No. M24413 CAS No. 461000-66-8

Eact is a selective and potent TMEM16A activator. It directly activates the TRPV1 channels in sensory nociceptors. Which also produces itch, acute nociception and thermal hypersensitivity.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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2MG	40	In Stock
5MG	65	In Stock
10MG	115	In Stock
25MG	240	In Stock
50MG	407	In Stock
100MG	599	In Stock
200MG	Get Quote	In Stock
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Biological Information

Product Name

Eact
Note

Research use only, not for human use.
Brief Description

Eact is a selective and potent TMEM16A activator. It directly activates the TRPV1 channels in sensory nociceptors. Which also produces itch, acute nociception and thermal hypersensitivity.
Description

Eact is a selective and potent TMEM16A activator. It directly activates the TRPV1 channels in sensory nociceptors. Which also produces itch, acute nociception and thermal hypersensitivity.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

Chloride Channel
Recptor

TMEM16A
Research Area

——
Indication

——

Chemical Information

CAS Number

461000-66-8
Formula Weight

428.5
Molecular Formula

C22H24N2O5S
Purity

>98% (HPLC)
Solubility

DMSO:50 mg/mL (116.69 mM; Need ultrasonic)
SMILES

COCCN(C1=NC(=CS1)C2=CC=CC=C2)C(=O)C3=CC(=C(C(=C3)OC)OC)OC
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Liu S, et al. Eact, a small molecule activator of TMEM16A, activates TRPV1 and elicits pain- and itch-related behaviours. Br J Pharmacol. 2016 Apr;173(7):1208-18.

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