Cart
sales@molnova.com
Home - Products - Membrane Transporter/Ion Channel - TRP/TRPV Channel - HC067047 Hydrochloride(883031-03-6 free base)

HC067047 Hydrochloride(883031-03-6 free base)

CAS No. 1481646-76-7

HC067047 Hydrochloride(883031-03-6 free base)( —— )

Catalog No. M23636 CAS No. 1481646-76-7

HC-067047 hydrochloride is a potent and selective TRPV4 antagonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 218 In Stock
5MG 172 In Stock
10MG 258 In Stock
25MG 426 In Stock
50MG 586 In Stock
100MG 792 In Stock
200MG 1051 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    HC067047 Hydrochloride(883031-03-6 free base)
  • Note
    Research use only, not for human use.
  • Brief Description
    HC-067047 hydrochloride is a potent and selective TRPV4 antagonist.
  • Description
    HC-067047 hydrochloride is a potent and selective TRPV4 antagonist. HC-067047 hydrochloride reversibly inhibited currents through the human, rat, and mouse TRPV4 orthologs with IC50 values of 486 nM, 133nM, and 17 nM, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    TRP/TRPV Channel
  • Recptor
    TRPV4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1481646-76-7
  • Formula Weight
    507.98
  • Molecular Formula
    C26H29ClF3N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(C1=C(C)N(CCCN2CCOCC2)C(C3=CC=CC=C3)=C1)NC4=CC=CC(C(F)(F)F)=C4.[H]Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Xing Y , Ming J , Liu T , et al. Decreased Expression of TRPV4 Channels in HEI-OC1 Cells Induced by High Glucose Is Associated with Hearing Impairment[J]. Yonsei medical journal, 2018, 59(9).
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • JC-229

    JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).

  • RN9893

    RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.

  • MSP3

    MSP3 is an agonist of TRPV1 (EC50 = 0.87 μM) and shows antinociceptive and neuroprotective effects.

Sign In Join Free