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DHPG
CAS No. 146255-66-5
DHPG( (RS)-3,5-DHPG )
Catalog No. M23623 CAS No. 146255-66-5
DHPG ((RS)-3,5-DHPG) is an effective antagonist of mGluR linked to phospholipase D.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 39 | In Stock |
|
| 10MG | 61 | In Stock |
|
| 25MG | 114 | In Stock |
|
| 50MG | 208 | In Stock |
|
| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameDHPG
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NoteResearch use only, not for human use.
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Brief DescriptionDHPG ((RS)-3,5-DHPG) is an effective antagonist of mGluR linked to phospholipase D.
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DescriptionDHPG ((RS)-3,5-DHPG) is an effective antagonist of mGluR linked to phospholipase D. It is an amino acid that can be used as a selective and potent agonist for Group I mGluR (mGluR 1 and mGluR 5) and has no effect on Group II or Group III mGluRs .
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In Vitro——
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In Vivo——
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Synonyms(RS)-3,5-DHPG
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PathwayNeuroscience
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TargetGluR
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RecptormGluR1
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Research Area——
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Indication——
Chemical Information
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CAS Number146255-66-5
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Formula Weight183.16
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Molecular FormulaC8H9NO4
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Purity>98% (HPLC)
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SolubilityDMSO: 1 mg/mL (5.46 mM; Need ultrasonic);H2O: 1 mg/mL (5.46 mM; Need ultrasonic)
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SMILESO=C(O)C(N)C1=CC(O)=CC(O)=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Ziyuglycoside II
Ziyuglycoside II has anticancer, and antitumor properties against gastric cancer and breast cancer cells, by cell cycle arrest and cell apoptosis.
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VU6012962
VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).
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Basimglurant
Basimglurant is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM). In competition binding experiments on human recombinant mGlu5, Basimglurant (RG7090) fully displaces [3H]-MPEP with a Ki of 35.6 nM and [3H]-ABP688 with a Ki of 1.4 nM. In HEK293 cells stably expressing human mGlu5, Basimglurant (RG7090) inhibits quisqualate induced Ca2+ mobilization with an IC50 of 7.0 nM and [3H]-inositolphosphate accumulation (IC50 of 5.9 nM).
