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ML 254
CAS No. 1428630-86-7
ML 254( —— )
Catalog No. M23588 CAS No. 1428630-86-7
ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricerca profile, and suitable dystrophia myotonica protein kinase (DMPK) properties for systemic dosing in rodents.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 89 | In Stock |
|
| 5MG | 69 | In Stock |
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| 10MG | 112 | In Stock |
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| 25MG | 259 | In Stock |
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| 50MG | 375 | In Stock |
|
| 100MG | 533 | In Stock |
|
| 200MG | 724 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameML 254
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NoteResearch use only, not for human use.
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Brief DescriptionML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricerca profile, and suitable dystrophia myotonica protein kinase (DMPK) properties for systemic dosing in rodents.
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DescriptionML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricerca profile, and suitable dystrophia myotonica protein kinase (DMPK) properties for systemic dosing in rodents.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayNeuroscience
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TargetGluR
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RecptormGluR5
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Research Area——
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Indication——
Chemical Information
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CAS Number1428630-86-7
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Formula Weight310.32
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Molecular FormulaC18H15FN2O2
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESCC1(COC1)NC(=O)C2=NC=C(C=C2)C#CC3=CC(=CC=C3)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zhou Y , Chun A , Gogliotti R D , et al. Pure Positive Allosteric Modulators (PAMs) of mGlu5 with Competitive MPEP-Site Interaction[M]// Probe Reports from the NIH Molecular Libraries Program. PubMed, 2010.
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