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Mutated EGFR-IN-1
CAS No. 1421372-66-8
Mutated EGFR-IN-1( Osimertinib analog )
Catalog No. M23574 CAS No. 1421372-66-8
Mutated EGFR-IN-1 is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant, and T790M resistance mutant.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 48 | In Stock |
|
| 50MG | 55 | In Stock |
|
| 100MG | 74 | In Stock |
|
| 200MG | 106 | In Stock |
|
| 500MG | 177 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMutated EGFR-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionMutated EGFR-IN-1 is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant, and T790M resistance mutant.
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DescriptionMutated EGFR-IN-1 is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant, and T790M resistance mutant.
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In Vitro——
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In Vivo——
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SynonymsOsimertinib analog
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PathwayAngiogenesis
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TargetEGFR
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RecptorEGFR (L858R)|EGFR (T790M)|EGFR(Exon 19 deletion/T790M)
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Research Area——
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Indication——
Chemical Information
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CAS Number1421372-66-8
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Formula Weight445.56
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Molecular FormulaC25H31N7O
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Purity>98% (HPLC)
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SolubilityDMSO: 75 mg/mL (168.33 mM)
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SMILESNC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Patent WO 2013014448 A2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer .
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