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Mefentrifluconazole

CAS No. 1417782-03-6

Mefentrifluconazole( —— )

Catalog No. M23572 CAS No. 1417782-03-6

Mefentrifluconazole is a potent, selective and orally active fungal CYP51 (Kd= 0.5 nM) inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 215 In Stock
5MG 188 In Stock
10MG 312 In Stock
25MG 511 In Stock
50MG 693 In Stock
100MG 830 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Mefentrifluconazole
  • Note
    Research use only, not for human use.
  • Brief Description
    Mefentrifluconazole is a potent, selective and orally active fungal CYP51 (Kd= 0.5 nM) inhibitor.
  • Description
    Mefentrifluconazole is a potent, selective and orally active fungal CYP51 (Kd= 0.5 nM) inhibitor, but shows less inhibitory activity on human aromatase (IC50=0.92 μM). Mefentrifluconazole is a novel azole derivative and used as an agrochemical broad-spectrum antifungal agent.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    P450
  • Recptor
    CYP51A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1417782-03-6
  • Formula Weight
    397.78
  • Molecular Formula
    C18H15ClF3N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 100 mg/mL (251.40 mM; Need ultrasonic)
  • SMILES
    OC(C)(C1=CC=C(OC2=CC=C(Cl)C=C2)C=C1C(F)(F)F)CN3N=CN=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tesh SA, et al. Innovative selection approach for a new antifungal agent mefentrifluconazole (Revysol?) and the impact upon its toxicity profile. Regul Toxicol Pharmacol.?2019?Aug;106:152-168.
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