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1-Ethynylnaphthalene
CAS No. 15727-65-8
1-Ethynylnaphthalene( —— )
Catalog No. M20721 CAS No. 15727-65-8
1-Ethynylnaphthalene is a selective inhibitor of cytochrome P450 IB1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | 33 | In Stock |
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Biological Information
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Product Name1-Ethynylnaphthalene
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NoteResearch use only, not for human use.
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Brief Description1-Ethynylnaphthalene is a selective inhibitor of cytochrome P450 IB1.
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Description1-Ethynylnaphthalene is a selective inhibitor of cytochrome P450 IB1.
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In Vitro1-Ethynylnaphthalene, selective inhibitor of cytochrome P450 IB1, does not affect 2-hydroxylation but inhibits 4-hydroxylation by 38%. At higher concentrations, 1-Ethynylnaphthalene inhibits 2-hydroxylation of 2-Hydroxylation of estradiol (E2) by ~30% and 4-hydroxylation of E2 by up to 80%.
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetP450
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RecptorCYP450 1B1
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Research Area——
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Indication——
Chemical Information
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CAS Number15727-65-8
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Formula Weight152.19
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Molecular FormulaC12H8
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL (821.34 mM)
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SMILESC#Cc1cccc2ccccc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Hammons G J Alworth W L Hopkins N E et al. 2-Ethynylnaphthalene as a mechanism-based inactivator of the cytochrome P-450 catalyzed N-oxidation of 2-naphthylamine[J]. Chemical Research in Toxicology 1989 2(6):367-374.
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