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HIV-1 Nef-IN-1

CAS No. 13728-56-8

HIV-1 Nef-IN-1( —— )

Catalog No. M23525 CAS No. 13728-56-8

HIV-1 Nef-IN-1 is an inhibitor of HIV-1 Nef protein. It efficiently competes for Nef-SH3Hck interactions(Kd : 6.7 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 29 In Stock
5MG 29 In Stock
10MG 48 In Stock
25MG 79 In Stock
50MG 122 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    HIV-1 Nef-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    HIV-1 Nef-IN-1 is an inhibitor of HIV-1 Nef protein. It efficiently competes for Nef-SH3Hck interactions(Kd : 6.7 μM).
  • Description
    HIV-1 Nef-IN-1 is an inhibitor of HIV-1 Nef protein. It efficiently competes for Nef-SH3Hck interactions(Kd : 6.7 μM).
  • In Vitro
    HIV-1 Nef-IN-1 (Compound D11; 20 μM) inhibits cell viability of COS7 cells, and the cell inhibition rate is 63.2%.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    HIV-1 Nef
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    13728-56-8
  • Formula Weight
    264.32
  • Molecular Formula
    C18H16O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    C1=CC=C2C(=C1)C=CC3=C2C=C(C=C3)CCCC(=O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Stéphane Betzi, et al. Protein protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein. Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19256-61.
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