Cart
sales@molnova.com
NH2-PEG6-Boc
CAS No. 1286281-32-0
NH2-PEG6-Boc( —— )
Catalog No. M23449 CAS No. 1286281-32-0
NH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 26 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNH2-PEG6-Boc
-
NoteResearch use only, not for human use.
-
Brief DescriptionNH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
-
DescriptionNH2-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG6-Boc is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
-
In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
-
In Vivo——
-
Synonyms——
-
PathwayPROTACs
-
TargetPROTAC
-
RecptorPEGs|Alkyl/ether|Non-cleavable
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1286281-32-0
-
Formula Weight409.51
-
Molecular FormulaC19H39NO8
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCN
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Foley CA, et al. Assessing the Cell Permeability of Bivalent Chemical Degraders Using the Chloroalkane Penetration Assay. ACS Chem Biol. 2020 Jan 17;15(1):290-295.
molnova catalog
related products
-
5-ETHYNYL-2'-DEOXYUR...
5-Ethynyl-2'-deoxyuridine (EdU) is a nucleoside analog of thymidine that is used to monitor de novo DNA synthesis through click chemistry.
-
Pyrroline-5-carboxyl...
Pyrroline-5-carboxylate sodium is a naturally occurring intermediate and a potent activator of redox-dependent metabolic pathways and a PROTAC linker.
-
Biotin-PEG3-acid
Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs.Biotin-PEG3-acid is a heterobiofunctional biotin PEG derivative containing a carboxylic acid group. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule.
