Sulfuretin

Research use only, not for human use.

Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 through the Nrf2/ARE and JNK/ERK signaling pathways.

Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 through the Nrf2/ARE and JNK/ERK signaling pathways.

Sulfuretin is one of the main flavonoids produced by Rhus verniciflua. Sulfuretin efficiently inhibits the infiltration of inflammatory cells and attenuates allergic airway inflammation.

Sulfuretin inhibits the inflammatory responses by suppressing the NF-κB pathway in type 1 diabetes models. Sulfuretin (40 μg/kg; single intraperitoneal injection 2 h after the last OVA challenge) suppresses ovalbumin (OVA)-induced chemotaxis and airway inflammation. Animal Model:Pathogen-free male BALB/c mice (7-8 weeks old)Dosage:40 μg/kg Administration:A single intraperitoneal injection was administered 2 h after the last OVA challengeResult:Suppressed OVA-induced chemotaxis and airway inflammation.

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Autophagy

Autophagy

(HO)-1

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120-05-8

270.24

C15H10O5

>98% (HPLC)

DMSO:10 mM

C1=CC(=C(C=C1/C=C\2/C(=O)C3=C(O2)C=C(C=C3)O)O)O

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(-20℃)

With Ice Pack

≥ 2 years