ELOVL6-IN-1

CAS No. 1185736-98-4

ELOVL6-IN-1( —— )

Catalog No. M23355 CAS No. 1185736-98-4

ELOVL6-IN-1 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse ELOVL6 activities.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 126 In Stock
5MG 116 In Stock
10MG 192 In Stock
25MG 314 In Stock
50MG 421 In Stock
100MG 578 In Stock
200MG 775 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ELOVL6-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    ELOVL6-IN-1 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse ELOVL6 activities.
  • Description
    ELOVL6-IN-1 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse ELOVL6 activities, with an IC50 value of 0.350 μM. ELOVL6-IN-1 inhibits ELOVL6 in a noncompetitive manner for malonyl-CoA (Ki=994 nM) and palmitoyl-CoA[1].
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ELOVL6
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1185736-98-4
  • Formula Weight
    495.49
  • Molecular Formula
    C27H24F3N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:45 mg/mL?(90.82 mM;?Need ultrasonic)
  • SMILES
    O=C1N(C2=CC=CC=C2)C3=C(C(C(C)(C)CC3)=O)C1(C4=C(C)NN(C5=CC=CC=C5)C4=O)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Shimamura K, et al. 5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione, a potent inhibitor for mammalian elongase of long-chain fatty acids family 6: examination of its potential utility as a pharmacological tool. J Pharmacol Exp Ther. 2009;330(1):249-256.
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