Cart
sales@molnova.com
SCH-37370
CAS No. 117796-52-8
SCH-37370( SCH 37370 | SCH37370 )
Catalog No. M23344 CAS No. 117796-52-8
SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 79 | In Stock |
|
| 5MG | 78 | In Stock |
|
| 10MG | 111 | In Stock |
|
| 25MG | 196 | In Stock |
|
| 50MG | 285 | In Stock |
|
| 100MG | 384 | In Stock |
|
| 200MG | 510 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSCH-37370
-
NoteResearch use only, not for human use.
-
Brief DescriptionSCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine.
-
DescriptionSCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine. Sch 37370 blocks the binding of [3H]pyrilamine to histamine-H1 receptors in rat brain membranes. Sch 37370 selectively inhibits PAF-induced aggregation of human platelets (IC50 : 0.6 mM) and also competes with PAF binding to specific sites in membrane preparations from human lungs (IC50 : 1.2 mM).
-
In Vitro——
-
In Vivo——
-
SynonymsSCH 37370 | SCH37370
-
PathwayOthers
-
TargetOther Targets
-
RecptorPAF
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number117796-52-8
-
Formula Weight352.86
-
Molecular FormulaC21H21ClN2O
-
Purity>98% (HPLC)
-
SolubilityDMSO:Soluble
-
SMILESCC(N(CC1)CCC1=C(c(cc1)c(CC2)cc1Cl)c1c2cccn1)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Kaminski JJ, Carruthers NI, Wong SC, Chan TM, Billah MM, Tozzi S, McPhail AT. Conformational considerations in the design of dual antagonists of platelet-activating factor (PAF) and histamine. Bioorg Med Chem. 1999 Jul;7(7):1413-23. PubMed PMID: 10465415.
molnova catalog
related products
-
Baohuoside II
IKarisoside A(Baohuoside II) is a flavonol glycoside from the Berberidaceae plant Epimedium, with anti-inflammatory activity.
-
[Sar1, Ile8]-Angiote...
[Sar1, Ile8]-Angiotensin II is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels. The biological activities of angiotensin II antagonists upon basal and angiotensin II-stimulated aldosterone production were evaluated in an isolated canine glomerulosa cell preparation.
-
Episyringaresinol
Episyringaresinol is a natural lignan isolated from Kalimeris indica.
