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SCH-37370
CAS No. 117796-52-8
SCH-37370( SCH 37370 | SCH37370 )
Catalog No. M23344 CAS No. 117796-52-8
SCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 79 | In Stock |
|
| 5MG | 78 | In Stock |
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| 10MG | 111 | In Stock |
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| 25MG | 196 | In Stock |
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| 50MG | 285 | In Stock |
|
| 100MG | 384 | In Stock |
|
| 200MG | 510 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSCH-37370
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NoteResearch use only, not for human use.
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Brief DescriptionSCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine.
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DescriptionSCH-37370 is an effective and orally active dual antagonist of platelet-activating factor and histamine. Sch 37370 blocks the binding of [3H]pyrilamine to histamine-H1 receptors in rat brain membranes. Sch 37370 selectively inhibits PAF-induced aggregation of human platelets (IC50 : 0.6 mM) and also competes with PAF binding to specific sites in membrane preparations from human lungs (IC50 : 1.2 mM).
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In Vitro——
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In Vivo——
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SynonymsSCH 37370 | SCH37370
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PathwayOthers
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TargetOther Targets
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RecptorPAF
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Research Area——
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Indication——
Chemical Information
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CAS Number117796-52-8
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Formula Weight352.86
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Molecular FormulaC21H21ClN2O
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Purity>98% (HPLC)
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SolubilityDMSO:Soluble
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SMILESCC(N(CC1)CCC1=C(c(cc1)c(CC2)cc1Cl)c1c2cccn1)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kaminski JJ, Carruthers NI, Wong SC, Chan TM, Billah MM, Tozzi S, McPhail AT. Conformational considerations in the design of dual antagonists of platelet-activating factor (PAF) and histamine. Bioorg Med Chem. 1999 Jul;7(7):1413-23. PubMed PMID: 10465415.
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