Cart
sales@molnova.com
CGS 15943
CAS No. 104615-18-1
CGS 15943( —— )
Catalog No. M23255 CAS No. 104615-18-1
CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 50 | In Stock |
|
| 2MG | 29 | In Stock |
|
| 5MG | 46 | In Stock |
|
| 10MG | 75 | In Stock |
|
| 25MG | 150 | In Stock |
|
| 50MG | 230 | In Stock |
|
| 100MG | 346 | In Stock |
|
| 200MG | 510 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCGS 15943
-
NoteResearch use only, not for human use.
-
Brief DescriptionCGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor.
-
DescriptionCGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor. In transfected CHO cells, its Ki for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM , respectively.
-
In VitroCell Viability Assay Cell Line:HLF, SK-Hep-1, HepG2 and PLC-PRF-5 cells Concentration:0 μM; 1 μM; 5 μM; 10 μM; 20 μM Incubation Time:24 hours Result:Inhibited growth of four distinct HCC cell lines.Western Blot Analysis Cell Line:HLF and Sk-Hep-1 cells Concentration:0 μM; 1 μM; 5 μM; 10 μM; 20 μM Incubation Time:24 hours Result:Inhibited the PI3K/Akt pathway in HLF and Sk-Hep-1 cells
-
In Vivo——
-
Synonyms——
-
PathwayEndocrinology/Hormones
-
TargetAChR
-
RecptorAdenosine A1?receptor|adenosine A2A receptor|adenosine A2B receptor|adenosine A3 receptor|p110γ|p110δ
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number104615-18-1
-
Formula Weight285.69
-
Molecular FormulaC13H8ClN5O
-
Purity>98% (HPLC)
-
SolubilityDMSO:12.22 mg/mL (42.77 mM; Need ultrasonic)
-
SMILESC1=COC(=C1)C2=NN3C(=N2)C4=C(C=CC(=C4)Cl)N=C3N
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Gao Y, et al. CGS 15943, an adenosine A2 receptor antagonist, reduces cerebral ischemic injury in the Mongolian gerbil. Life Sci. 1994;55(3):PL61-5.
molnova catalog
related products
-
Syn-Ake acetate
Syn-Ake acetate is a muscarinic acetylcholine receptor antagonist.
-
α-Bungarotoxin
Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs). Prevents opening of nicotinic receptor-associated ion channels and is selective for α7 receptors over α3β4 receptors (IC50 values are 1.6 nM and > 3 μM respectively).
-
(-)-Cotinine
Cotinine is an alkaloid found in tobacco and is also the predominant metabolite of nicotine, used as a biomarker for exposure to tobacco smoke.
