Cart
sales@molnova.com
Home - Products - Endocrinology/Hormones - AChR - CGS 15943

CGS 15943

CAS No. 104615-18-1

CGS 15943( —— )

Catalog No. M23255 CAS No. 104615-18-1

CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 50 In Stock
2MG 29 In Stock
5MG 46 In Stock
10MG 75 In Stock
25MG 150 In Stock
50MG 230 In Stock
100MG 346 In Stock
200MG 510 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    CGS 15943
  • Note
    Research use only, not for human use.
  • Brief Description
    CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor.
  • Description
    CGS 15943 is an orally bioavailable non-xanthine antagonist of Adenosine Receptor. In transfected CHO cells, its Ki for human A1, A2A, A2B, and A3 Adenosine Receptors are 3.5, 4.2, 16, and 50 nM , respectively.
  • In Vitro
    Cell Viability Assay Cell Line:HLF, SK-Hep-1, HepG2 and PLC-PRF-5 cells Concentration:0 μM; 1 μM; 5 μM; 10 μM; 20 μM Incubation Time:24 hours Result:Inhibited growth of four distinct HCC cell lines.Western Blot Analysis Cell Line:HLF and Sk-Hep-1 cells Concentration:0 μM; 1 μM; 5 μM; 10 μM; 20 μM Incubation Time:24 hours Result:Inhibited the PI3K/Akt pathway in HLF and Sk-Hep-1 cells
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    Adenosine A1?receptor|adenosine A2A receptor|adenosine A2B receptor|adenosine A3 receptor|p110γ|p110δ
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    104615-18-1
  • Formula Weight
    285.69
  • Molecular Formula
    C13H8ClN5O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:12.22 mg/mL (42.77 mM; Need ultrasonic)
  • SMILES
    C1=COC(=C1)C2=NN3C(=N2)C4=C(C=CC(=C4)Cl)N=C3N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gao Y, et al. CGS 15943, an adenosine A2 receptor antagonist, reduces cerebral ischemic injury in the Mongolian gerbil. Life Sci. 1994;55(3):PL61-5.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Piperidolate hydroch...

    Piperidolate hydrochloride is an antimuscarinic?could restrain the abnormal activity caused by acetylcholine.?inhibits intestinal cramp induced by acetylcholine (rats and dogs).

  • 5-Hydroxy-1,7-diphen...

    5-Hydroxy-1, 7-diphenyl-6-hepten-3-one has antioxidant activity.

  • Temephos

    Temefos is an organophosphate larvicide, used to treat water infested with disease-carrying insects including mosquitoes, midges, and black fly larvae.

Sign In Join Free