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Cetirizine Impurity B dihydrochloride
CAS No. 1000690-91-4
Cetirizine Impurity B dihydrochloride( De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride )
Catalog No. M23207 CAS No. 1000690-91-4
Cetirizine Impurity B dihydrochloride is an impurity of Cetirizine dihydrochloride.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 25MG | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameCetirizine Impurity B dihydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionCetirizine Impurity B dihydrochloride is an impurity of Cetirizine dihydrochloride.
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DescriptionCetirizine Impurity B dihydrochloride is an impurity of Cetirizine dihydrochloride. Cetirizine, a second-generation antihistamine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response.
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In Vitro——
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In Vivo——
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SynonymsDe(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride
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PathwayGPCR/G Protein
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TargetHistamine Receptor
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RecptorH1 receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1000690-91-4
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Formula Weight417.76
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Molecular FormulaC19H23Cl3N2O2
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESO=C(O)CN1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1.[H]Cl.[H]Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Sodium butanoate
Sodium Butyrate(Butanoic acid sodium salt) has been reported to cause hyperacetylation of histones due to its role as a histone deacetylase (HDAC) inhibitor (IC50 values are 0.3, 0.4, 0.3, mM for HDAC1, 2 and 7 respectively).
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GSK189254A
GSK189254A is a potent and specific histamine H3 receptor antagonist (pKi values: 9.59-9.90 and 8.51-9.17 for human and rat H3).
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JNJ-5207852 dihydroc...
JNJ-5207852 is a novel, non-imidazole histamine H3 receptor antagonist, with high affinity at the rat (pKi=8.9) and human (pKi=9.24) H3 receptor. JNJ-5207852 is a potent dibasic amine antagonist that binds potently to rat H3 receptors (Ki=1.2?nm), and has good brain penetration. In ex vivo binding studies in mice, the compound had an ED50 of 0.13?mg?kg?1, subcutaneously.
