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Cyclo(-RGDfK) TFA
CAS No. 500577-51-5
Cyclo(-RGDfK) TFA( —— )
Catalog No. M22892 CAS No. 500577-51-5
Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 164 | In Stock |
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| 5MG | 96 | In Stock |
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| 10MG | 160 | In Stock |
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| 25MG | 282 | In Stock |
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| 50MG | 384 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCyclo(-RGDfK) TFA
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NoteResearch use only, not for human use.
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Brief DescriptionCyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).
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DescriptionCyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetIntegrin
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RecptorαVβ3 integrin
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Research Area——
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Indication——
Chemical Information
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CAS Number500577-51-5
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Formula Weight717.69
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Molecular FormulaC29H42F3N9O9
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (139.34 mM; Need ultrasonic); H2O:33.33 mg/mL (46.44 mM; Need ultrasonic)
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SMILESC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCN=C(N)N)CCCCN)CC2=CC=CC=C2)CC(=O)O.C(=O)(C(F)(F)F)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Fibronectin CS1 Pept...
he connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. CS1 peptide of fibronectin, which lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastasis models. The use of Fibronectin CS1 Peptide might offer a promising therapeutic approach for combating and preventing cancer metastasis.
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Abciximab
Abciximab (C7E3) is a mouse/human chimeric monoclonal antibody that is a potent glycoprotein IIb/IIIa inhibitor.
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Cilengitide trifluor...
Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.
