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CBP-IN-1
CAS No. 2222941-37-7
CBP-IN-1( —— )
Catalog No. M22843 CAS No. 2222941-37-7
CBP-IN-1 is a potent inhibitor of p300/CBP bromodomain.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 174 | In Stock |
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| 2MG | 88 | In Stock |
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| 5MG | 147 | In Stock |
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| 10MG | 264 | In Stock |
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| 25MG | 558 | In Stock |
|
| 50MG | 780 | In Stock |
|
| 100MG | 1051 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCBP-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionCBP-IN-1 is a potent inhibitor of p300/CBP bromodomain.
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DescriptionCBP-IN-1 is a potent inhibitor of p300/CBP bromodomain.
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In Vitro——
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In VivoAnimal Model:Noncastrated male athymic nude mice Dosage:10-30 mg/kg Administration:Oral gavage; at 10 or 20 mg/kg daily (QD) or at 30 mg/kg every other day (QOD) for 28 days Result:Affected tumor growth at 10 mg/kg daily, 20 mg/kg daily, and 30 mg/kg every other day.
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetEpigenetic Reader Domain
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Recptorp300/CBP
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Research Areacancer
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IndicationHaematological Malignancy|Acute Myeloid Leukemia|Non Hodgkin Lymphoma|Multiple Myeloma
Chemical Information
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CAS Number2222941-37-7
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Formula Weight534.6
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Molecular FormulaC30H32F2N4O3
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (187.06 mM; Need ultrasonic)
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SMILESO=C1N(C2=CC=C(F)C(F)=C2)[C@H](C3=NC4=CC(C5=C(C)ON=C5C)=CC=C4N3[C@H]6CC[C@H](OC)CC6)CCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Neil Anthony Pegg, et al. Pharmaceutical compounds. WO2018073586A1.
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