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Phytohemagglutinin

CAS No. 9008-97-3

Phytohemagglutinin( PHA-M )

Catalog No. M22701 CAS No. 9008-97-3

Phytohemagglutinin is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 40 In Stock
10MG 65 In Stock
25MG 117 In Stock
50MG 184 In Stock
100MG 296 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    Phytohemagglutinin
  • Note
    Research use only, not for human use.
  • Brief Description
    Phytohemagglutinin is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3.
  • Description
    Phytohemagglutinin is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3.
  • In Vitro
    Phytohemagglutinin (PHA-M) binds to the membranes of T-cells, stimulates metabolic activity, cell division, and involves inflammatory pathways.Apoptosis Analysis Cell Line:A20 (mouse B cell lymphoma, TLB-208), BW5147.3 (mouse T cell lymphoma, TIB-47), EL4 (mouse T cell lymphoma, TIB-39) Concentration:20 μg/ml Incubation Time:20-48 hours Result:Enhanced apoptosis in A20, BW5147.3 and EL4 cells.
  • In Vivo
    Phytohemagglutinin (100 μg; i.p.; daily for 2 days) inhibits A20 tumor growth. Animal Model:CB17-SCID Mice (bearing A20 cells)Dosage:100 μg Administration:I.p.; daily for 2 days Result:Inhibited A20 tumor growth.
  • Synonyms
    PHA-M
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    9008-97-3
  • Formula Weight
    ——
  • Molecular Formula
    ——
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:50 mg/mL (Need ultrasonic);DMSO:< 1 mg/mL (insoluble or slightly soluble)
  • SMILES
    N/A
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Movafagh A, et al. The Significance Application of Indigenous Phytohemagglutinin (PHA) Mitogen on Metaphase and Cell Culture Procedure. Iran J Pharm Res. 2011 Fall;10(4):895-903.
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