Cart
sales@molnova.com
Phytohemagglutinin
CAS No. 9008-97-3
Phytohemagglutinin( PHA-M )
Catalog No. M22701 CAS No. 9008-97-3
Phytohemagglutinin is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 40 | In Stock |
|
| 10MG | 65 | In Stock |
|
| 25MG | 117 | In Stock |
|
| 50MG | 184 | In Stock |
|
| 100MG | 296 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePhytohemagglutinin
-
NoteResearch use only, not for human use.
-
Brief DescriptionPhytohemagglutinin is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3.
-
DescriptionPhytohemagglutinin is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3.
-
In VitroPhytohemagglutinin (PHA-M) binds to the membranes of T-cells, stimulates metabolic activity, cell division, and involves inflammatory pathways.Apoptosis Analysis Cell Line:A20 (mouse B cell lymphoma, TLB-208), BW5147.3 (mouse T cell lymphoma, TIB-47), EL4 (mouse T cell lymphoma, TIB-39) Concentration:20 μg/ml Incubation Time:20-48 hours Result:Enhanced apoptosis in A20, BW5147.3 and EL4 cells.
-
In VivoPhytohemagglutinin (100 μg; i.p.; daily for 2 days) inhibits A20 tumor growth. Animal Model:CB17-SCID Mice (bearing A20 cells)Dosage:100 μg Administration:I.p.; daily for 2 days Result:Inhibited A20 tumor growth.
-
SynonymsPHA-M
-
PathwayApoptosis
-
TargetApoptosis
-
RecptorApoptosis
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number9008-97-3
-
Formula Weight——
-
Molecular Formula——
-
Purity>98% (HPLC)
-
SolubilityH2O:50 mg/mL (Need ultrasonic);DMSO:< 1 mg/mL (insoluble or slightly soluble)
-
SMILESN/A
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Movafagh A, et al. The Significance Application of Indigenous Phytohemagglutinin (PHA) Mitogen on Metaphase and Cell Culture Procedure. Iran J Pharm Res. 2011 Fall;10(4):895-903.
molnova catalog
related products
-
NSC 745887
NSC 745887 is a small molecule that effectively inhibits the proliferation of various cancers by trapping DNA-topoisomerase cleavage.
-
Sodium Oxamate
Sodium Oxamate is an LDH inhibitor.?Sodium oxamate (SO) induces G2/M cell cycle arrest via downregulation of the CDK1/cyclin B1 pathway and promotes apoptosis through enhancement of mitochondrial ROS generation.
-
SPOP-IN-6lc
SPOP-IN-6lc is a potent SPOP inhibitor with multiple roles in cancer, oncostatic in a variety of tumors, but functions as an oncogene in renal cancer.SPOP-IN-6lc can be used to study cell signaling and apoptosis.
