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Zoliflodacin (b)
CAS No. 1245732-48-2
Zoliflodacin (b)( —— )
Catalog No. M22412 CAS No. 1245732-48-2
Zoliflodacin is a new antibiotic that inhibits DNA biosynthesis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 272 | In Stock |
|
| 10MG | 408 | In Stock |
|
| 25MG | 735 | In Stock |
|
| 50MG | 1103 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameZoliflodacin (b)
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NoteResearch use only, not for human use.
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Brief DescriptionZoliflodacin is a new antibiotic that inhibits DNA biosynthesis.
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DescriptionZoliflodacin is a new antibiotic that inhibits DNA biosynthesis.
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In Vitro——
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In VivoAnimal Model:MCF-7 human breast cancers growing in miceDosage:56 mg/kg Administration:IV; 2 daily; 49 days Result:Alone was able to produce significant (>50%) tumor regression. This regression was stabilized when combined with daily dosing with the oral HDAC4 inhibitor, Tasquinimod (10 mg/kg/d; oral).Animal Model:BALB/c miceDosage:67 mg/kg (Pharmacokinetic Analysis)Administration:IV; a single dose Result:Had a half-life of 4.9 hours.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1245732-48-2
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Formula Weight1409.5
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Molecular FormulaC66H100N6O27?
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Purity>98% (HPLC)
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Solubility——
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SMILESCCCCCCCC(=O)O[C@H]1[C@H]2C(=C([C@@H]1OC(=O)/C(=C\C)/C)C)[C@H]3[C@]([C@H](C[C@]2(C)OC(=O)C)OC(=O)CCCCCCCCCCCNC(=O)C[C@@H](C(=O)N[C@@H](CCC(=O)N[C@@H](CCC(=O)N[C@@H](CCC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O)C(=O)O)C(=O)O)N)([C@](C(=O)O3)(C)O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Taylor S N , Marrazzo J , Batteiger B E , et al. Single-Dose Zoliflodacin (ETX0914) for Treatment of Urogenital Gonorrhea[J]. New England Journal of Medicine, 2018, 379(19):1835-1845.
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