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FOY 251

CAS No. 71079-09-9

FOY 251( —— )

Catalog No. M22400 CAS No. 71079-09-9

FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.FOY-251, an active metabolite of camostat mesilate, on sodium transport in the mouse cortical collecting duct cell line (M-1 cells) and on blood pressure in Dahl salt-sensitive rats.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 128 In Stock
5MG 112 In Stock
10MG 186 In Stock
25MG 317 In Stock
50MG 439 In Stock
100MG 625 In Stock
200MG Get Quote In Stock
500MG 1237 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    FOY 251
  • Note
    Research use only, not for human use.
  • Brief Description
    FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.FOY-251, an active metabolite of camostat mesilate, on sodium transport in the mouse cortical collecting duct cell line (M-1 cells) and on blood pressure in Dahl salt-sensitive rats.
  • Description
    FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.FOY-251, an active metabolite of camostat mesilate, on sodium transport in the mouse cortical collecting duct cell line (M-1 cells) and on blood pressure in Dahl salt-sensitive rats. Treatment with camostat mesilate or FOY-251 decreased equivalent current (Ieq) in M-1 cells in a dose-dependent manner and inhibited the protease activity of prostasin in vitro.
  • In Vitro
    FOY-251 represents a dose-dependent inhibition of equivalent current in M-1 cells.FOY-251 inhibits the proteolytic activity of prostasin.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    proteinase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    71079-09-9
  • Formula Weight
    409.41
  • Molecular Formula
    C17H19N3O7S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 20 mg/mL (48.85 mMul)
  • SMILES
    CS(O)(=O)=O.NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CC(O)=O)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Maekawa A , Kakizoe Y , Miyoshi T , et al. Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension[J]. Journal of Hypertension, 2009, 27(1):181.
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