PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.

3-O-β-D-Xylopyranosyl-(1→3)-α-L-Rhamnopyranosyl-(1→4)-α-L-arabinopyranosyl hederagenin-28-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester

Mitazalimab (ADC-1013; JNJ-64457107) is an FcγR-dependent CD40 agonist that targets tumors by activating antigen-presenting cells like dendritic cells (DC), initiating tumor-reactive T cells, promoting tumor-specific T cell infiltration and destruction of tumors, and remodeling the tumor-infiltrating myeloid microenvironment .