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6-Nitroveratraldehyde
CAS No. 20357-25-9
6-Nitroveratraldehyde( DMNB )
Catalog No. M22201 CAS No. 20357-25-9
6-Nitroveratraldehyde is DNA-dependent protein kinase (DNA-PK) inhibitor with IC50 of 15 μM, an enzyme involved in the non-homologous end-joining (NHEJ) pathway of double-stranded DNA break (DSB) repair in human cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | 27 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product Name6-Nitroveratraldehyde
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NoteResearch use only, not for human use.
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Brief Description6-Nitroveratraldehyde is DNA-dependent protein kinase (DNA-PK) inhibitor with IC50 of 15 μM, an enzyme involved in the non-homologous end-joining (NHEJ) pathway of double-stranded DNA break (DSB) repair in human cells.
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Description6-Nitroveratraldehyde is DNA-dependent protein kinase (DNA-PK) inhibitor with IC50 of 15 μM, an enzyme involved in the non-homologous end-joining (NHEJ) pathway of double-stranded DNA break (DSB) repair in human cells.
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In Vitro——
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In Vivo——
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SynonymsDMNB
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PathwayOthers
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TargetOther Targets
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RecptorDNA-dependent protein kinase
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Research Area——
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Indication——
Chemical Information
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CAS Number20357-25-9
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Formula Weight211.17
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Molecular FormulaC9H9NO5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (473.55 mM)
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SMILESCOc1cc(C=O)c(cc1OC)[N+](=O)[O-]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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neo-gambogic acid
Neogambogic acid an active ingredient in garcinia can inhibit the growth of some solid tumors and result in an anticancer effect it may be responsible for the inhibition of proliferation of human breast cancer cell line MCF-7 cells.
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(-)-Epiafzelechin
(-)-Epiafzelechin exhibits significant anti-inflammatory activity on carrageenin-induced mouse paw edema, it exhibits a dose-dependent inhibition on the COX activity with an IC50 value of 15 microM, it exhibits about 3-fold weaker inhibitory potency on the enzyme activity than indomethacin as a positive control.
