Anthracene-9-carboxylic acid

CAS No. 723-62-6

Anthracene-9-carboxylic acid( —— )

Catalog No. M22198 CAS No. 723-62-6

Anthracene-9-carboxylic acid is an inhibitor of chloride transport with a moderate to strong inhibitory action on PKA activated cardiac IcI.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Anthracene-9-carboxylic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Anthracene-9-carboxylic acid is an inhibitor of chloride transport with a moderate to strong inhibitory action on PKA activated cardiac IcI.
  • Description
    Anthracene-9-carboxylic acid is an inhibitor of chloride transport with a moderate to strong inhibitory action on PKA activated cardiac IcI.
  • In Vitro
    Anthracene-9-carboxylic acid causes a voltage-dependent block of outward currents in HEK 293T cells and inhibits a larger fraction of the current as depolarization increased.Anthracene-9-carboxylic acid induces a strong potentiation of tail currents measured at -100 mV after depolarizing voltages, as well as a prolongation of the deactivation kinetics in HEK 293T.Anthracene-9-carboxylic acid (500 μM, rabbit pulmonary artery smooth muscle cells) produces a small inhibition of the maximum outward Cl- current at +70 mV (21±10%) but augmented the amplitude of the instantaneous inward relaxation at -80 mV by 321±34%.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Cl-transport
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    723-62-6
  • Formula Weight
    222.24
  • Molecular Formula
    C15H10O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:22.22 mg/mL (100 mM)
  • SMILES
    OC(=O)c2c1ccccc1cc3ccccc23
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Villegas-Navarro A, Jiménez-Salas Z, Reyes JL. Anthracene-9-carboxylic acid and haematological and biochemical variables in the rat[J]. Archives Internationales De Pharmacodynamie Et De Thérapie, 1989, 302(302):290.
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