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Irigenin

CAS No. 548-76-5

Irigenin( —— )

Catalog No. M18785 CAS No. 548-76-5

Irigenin has antifungal activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 42 In Stock
5MG 38 In Stock
10MG 61 In Stock
25MG 112 In Stock
50MG 179 In Stock
100MG 272 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Irigenin
  • Note
    Research use only, not for human use.
  • Brief Description
    Irigenin has antifungal activity.
  • Description
    Irigenin has antifungal activity.
  • In Vitro
    Irigenin specifically targets α9β1 and α4β1 integrin binding sites on Extra Domain A (EDA) comprising LEU46, PHE47, PRO48, GLU58, LEU59 and GLN60 in its C-C loop. Irigenin binds to the C-C loop of EDA, thereby blocking its interaction with integrins on the cell surface and thus abrogating subsequent Epithelial-Mesenchymal transition.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    NF-κB
  • Research Area
    Cancer|Infection|Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    548-76-5
  • Formula Weight
    360.32
  • Molecular Formula
    C18H16O8
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (277.54 mM)
  • SMILES
    COc1cc(cc(c1OC)O)c1coc2cc(c(c(c2c1=O)O)OC)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kwang Seok Ahn, et al. Inhibitory effects of Irigenin from the rhizomes of Belamcanda chinensis on nitric oxide and prostaglandin E2 production in murine macrophage RAW 264.7 cells. 2006, 78(20): 2336-2342.
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