Cart
sales@molnova.com
Linoleoyl Ethanolamide
CAS No. 68171-52-8
Linoleoyl Ethanolamide( —— )
Catalog No. M21989 CAS No. 68171-52-8
Linoleoyl Ethanolamide is an endocannabinoid agent. It acts by binding to TRPV1 increasing ERK phosphorylation and AP-1 dependent transcription in CB-receptor in an independent manner.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 73 | In Stock |
|
| 5MG | 59 | In Stock |
|
| 10MG | 87 | In Stock |
|
| 25MG | 159 | In Stock |
|
| 50MG | 233 | In Stock |
|
| 100MG | 340 | In Stock |
|
| 200MG | 511 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameLinoleoyl Ethanolamide
-
NoteResearch use only, not for human use.
-
Brief DescriptionLinoleoyl Ethanolamide is an endocannabinoid agent. It acts by binding to TRPV1 increasing ERK phosphorylation and AP-1 dependent transcription in CB-receptor in an independent manner.
-
DescriptionLinoleoyl Ethanolamide is an endocannabinoid agent. It acts by binding to TRPV1 increasing ERK phosphorylation and AP-1 dependent transcription in CB-receptor in an independent manner.
-
In VitroLinoleoyl ethanolamide competitivelyinhibitsthehydrolysisofanandamide and maybeinvolvedintheregulationoffoodintakebyselectiveprolongationoffeedinglatencyandpost-mealinterval.
-
In VivoLinoleoyl ethanolamide (0.1 mg-0.2 mg; challenged by painting the inner and outer surfaces of both sides of their ears) suppresses DNFB-induced ear swelling in BALB/c mice.
-
Synonyms——
-
PathwayMembrane Transporter/Ion Channel
-
TargetTRP/TRPV Channel
-
RecptorTRPV1
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number68171-52-8
-
Formula Weight323.52
-
Molecular FormulaC20H37NO2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCO
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
JNJ-17203212
A potent, selective and orally bioavailable TRPV1 receptor antagonist with IC50 of 65 nM and 102 nM for hTRPV1 and rTRPV1, respectively.
-
Pyr6
Pyr6 is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influx inhibition in thapsigargin depleted native RBL-2H3 cells).Pyr6 is an inhibitor of Ca2+ entry, which displays higher potency to inhibit Ca2+ entry mediated by CRAC channel than by TRPC3.Pyr3 is selective inhibitor of TRPC3, inhibited Orai1- and TRPC3-mediated Ca(2+) entry and currents as well as mast cell activation with similar potency.?
-
Mogroside V
Mogroside V is a widely used sweetener, has in vitro AMPK activating effect, it also has anti-inflammatory potential in murine macrophages and a murine ear edema model, and has the potential to protect against LPS-induced airway inflammation in a model of ALI.
