Pratosartan

CAS No. 153804-05-8

Pratosartan( FW 7203 | KD 3-671 | KT 3671 )

Catalog No. M21854 CAS No. 153804-05-8

Pratosartan, which is an orally active angiotensin II (AII) antagonist, exhibiting selective and potent antagonistic activity to AT1 subtype. Pratosartan is a new angiotensin II type 1 receptor blocker.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Pratosartan
  • Note
    Research use only, not for human use.
  • Brief Description
    Pratosartan, which is an orally active angiotensin II (AII) antagonist, exhibiting selective and potent antagonistic activity to AT1 subtype. Pratosartan is a new angiotensin II type 1 receptor blocker.
  • Description
    Pratosartan, which is an orally active angiotensin II (AII) antagonist, exhibiting selective and potent antagonistic activity to AT1 subtype. Pratosartan is a new angiotensin II type 1 receptor blocker. Pratosartan is an effective and well tolerated antihypertensive drug, and may has beneficial effect on hypertensive patients with some metabolic disorders.
  • In Vitro
    Pratosartan, which is an orally active angiotensin II (AII) antagonist, exhibiting selective and potent antagonistic activity to AT1 subtype. Pratosartan is a new angiotensin II type 1 receptor blocker. Pratosartan is an effective and well tolerated antihypertensive drug, and may has beneficial effect on hypertensive patients with some metabolic disorders.
  • In Vivo
    ——
  • Synonyms
    FW 7203 | KD 3-671 | KT 3671
  • Pathway
    GPCR/G Protein
  • Target
    Angiotensin Receptor
  • Recptor
    angiotensin II receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    153804-05-8
  • Formula Weight
    426.51
  • Molecular Formula
    C??H??N?O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1CCCCC2=C1N(CC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3)C(CCC)=N2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sonegawa M, et al. Synthesis and pharmacological activity of the metabolites of Pratosartan. Chem Pharm Bull (Tokyo). 2006 Jun;54(6):782-7. 2. Ogihara T, et al. Clinical efficacy of a new angiotensin II type 1 receptor blocker, pratosartan, in hypertensive patients. Hypertens Res. 2008 Feb;31(2):281-7.
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