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Sulforaphene

CAS No. 592-95-0

Sulforaphene( —— )

Catalog No. M21772 CAS No. 592-95-0

Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 60 In Stock
2MG 38 In Stock
5MG 61 In Stock
10MG 93 In Stock
25MG 170 In Stock
50MG 249 In Stock
100MG 370 In Stock
200MG 542 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Sulforaphene
  • Note
    Research use only, not for human use.
  • Brief Description
    Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M.
  • Description
    Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF‐κB and other signals.
  • In Vitro
    Western Blot Analysis Cell Line:HepG2 and Hep3B cell Concentration:0-40 μM Incubation Time:48 h Result:Increased Bax expression and reduced Bcl-2 expression.Inhibited expression of NF-??B-dependent genes (COX-2, iNos, and cyclinD1).
  • In Vivo
    Animal Model:Mouse HCT116 xenograft model Dosage:1 and 5 mg/kg Administration:i.p., everyday Result:Inhibited tumor growth, and increased CDK1, MK2, and p38 phosphorylation.
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    592-95-0
  • Formula Weight
    175.27
  • Molecular Formula
    O=S(/C=C/CCN=C=S)C
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 100 mg/mL (570.55 mM; Need ultrasonic)
  • SMILES
    O=S(/C=C/CCN=C=S)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kuang P, et al. Separation and purification of sulforaphene from radish seeds using macroporous resin and preparative high-performance liquid chromatography. Food Chem. 2013 Jan 15;136(2):342-7. 2. Anita M. Brinker, et al. Herbicidal activity of sulforaphene from stock (Matthiola incana). Journal of Chemical Ecology. Vol. 19. No. 10, 1993. 3. Mondal A, et al. Sulforaphene promotes Bax/Bcl2, MAPK-dependent human gastric cancer AGS cells apoptosis and inhibits migration via EGFR, p-ERK1/2 down-regulation. General Physiology and Biophysics, 27 Nov 2015, 35(1):25-34.
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