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BSJ-03-123
CAS No. 2361493-16-3
BSJ-03-123( —— )
Catalog No. M21744 CAS No. 2361493-16-3
BSJ-03-123 is a potent and novel CDK6-selective small-molecule degrader (PROTAC).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 116 | In Stock |
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| 5MG | 187 | In Stock |
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| 10MG | 274 | In Stock |
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| 25MG | 432 | In Stock |
|
| 50MG | 578 | In Stock |
|
| 100MG | 826 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1665 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBSJ-03-123
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NoteResearch use only, not for human use.
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Brief DescriptionBSJ-03-123 is a potent and novel CDK6-selective small-molecule degrader (PROTAC).
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DescriptionBSJ-03-123 is a potent and novel CDK6-selective small-molecule degrader (PROTAC).
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In VitroBSJ-03-123 (BSJ) causes a pronounced anti-proliferative effect in CDK6-dependent AML cell lines by inducing a G1 cell-cycle arrest without a measurable increase in apoptosis.
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In Vivo——
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Synonyms——
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PathwayPROTACs
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TargetPROTAC
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number2361493-16-3
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Formula Weight937.01
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Molecular FormulaC??H??N??O??
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (106.72 mM)
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SMILESO=C(C(C(C)=O)=C1C)N(C2CCCC2)C3=C1C=NC(NC4=CC=C(N5CCN(CCOCCOCCOCCNC(COC6=CC=CC7=C6C(N(C8C(NC(CC8)=O)=O)C7=O)=O)=O)CC5)C=N4)=N3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Brand M, et al. Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML. Cell Chem Biol. 2019 Feb 21;26(2):300-306.e9.
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