Cart
sales@molnova.com
Pamoic acid
CAS No. 130-85-8
Pamoic acid( —— )
Catalog No. M21619 CAS No. 130-85-8
Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1G | 37 | Get Quote |
|
Biological Information
-
Product NamePamoic acid
-
NoteResearch use only, not for human use.
-
Brief DescriptionPamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
-
DescriptionPamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetGPR
-
RecptorGPR35
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number130-85-8
-
Formula Weight388.37
-
Molecular FormulaC23H16O6
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 50 mg/mL (128.74 mM)
-
SMILESOC(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc23)C(O)=O)c1O
-
Chemical Name44'-Methylenebis(3-hydroxy-2-naphthoic acid)
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Zhao P Sharir H Kapur A et al. Targeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and Arrestin2 with Antinociceptive Activity[J]. Molecular Pharmacology 2010 78(4):560-568.
molnova catalog
related products
-
BMS-903452
BMS-903452 is a potent and selective GPR119 agonist with an EC50 of 14 nM, indicated for the treatment of acute and chronic rodent diabetes.
-
APD 668
APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119 respectively.
-
ZK 756326
ZK 756326 is a selective, non-peptide CCR8 chemokine receptor agonist (IC50: 1.8 μM, in human; 2.6?μM, in mouse).
