Pamoic acid( —— )

Catalog No. M21619 CAS No. 130-85-8

Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.

Purity : >98% (HPLC)

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Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	28	Get Quote
100MG	Get Quote	Get Quote
200MG	Get Quote	Get Quote
500MG	Get Quote	Get Quote
1G	27	Get Quote

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Biological Information

Product Name

Pamoic acid
Note

Research use only, not for human use.
Brief Description

Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
Description

Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

GPR
Recptor

GPR35
Research Area

——
Indication

——

Chemical Information

CAS Number

130-85-8
Formula Weight

388.37
Molecular Formula

C23H16O6
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (128.74 mM)
SMILES

OC(=O)c1cc2ccccc2c(Cc2c(O)c(cc3ccccc23)C(O)=O)c1O
Chemical Name

44'-Methylenebis(3-hydroxy-2-naphthoic acid)

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Zhao P Sharir H Kapur A et al. Targeting of the Orphan Receptor GPR35 by Pamoic Acid: A Potent Activator of Extracellular Signal-Regulated Kinase and Arrestin2 with Antinociceptive Activity[J]. Molecular Pharmacology 2010 78(4):560-568.

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